• Telomerase-Activating Longevity Peptide – Epithalon (Ala-Glu-Asp-Gly) upregulates TERT gene expression to activate telomerase, the enzyme that lengthens telomeres and may slow cellular aging
• Clinically Studied Anti-Aging Compound – Backed by 25+ years of research at the St. Petersburg Institute of Bioregulation and Gerontology showing telomere lengthening of 33-42% in human fibroblasts
• Pineal Gland Function Support – Derived from pineal epithalamus extract, helps restore melatonin production and normalize circadian rhythm in aging individuals
• Cellular Health & DNA Protection – Provides antioxidant, neuroprotective, and antimutagenic effects that support healthy cellular function and genomic stability
• Research-Grade Bioregulator – Synthetic tetrapeptide bioidentical to naturally occurring pineal peptide, extensively studied for geroprotective and neuroendocrine effects
Epithalon: The Telomerase-Activating Longevity Peptide
Epithalon (also spelled Epitalon; sequence: Ala-Glu-Asp-Gly or AEDG) is a synthetic four-amino-acid peptide that represents one of the most scientifically compelling compounds in longevity research. Originally derived from epithalamus extracts of the pineal gland by Russian scientist Professor Vladimir Khavinson, this bioregulator peptide has been studied for over 25 years for its unique ability to activate telomerase—the enzyme responsible for maintaining and lengthening telomeres, the protective caps at the ends of chromosomes that shorten with each cell division.
Understanding Telomeres & Cellular Aging
Telomeres function as protective “caps” on chromosome ends, similar to the plastic tips on shoelaces. Each time a cell divides, telomeres naturally shorten. When telomeres become critically short, cells enter senescence (stop dividing) or die—a process considered a fundamental mechanism of biological aging. Telomerase is the enzyme that can rebuild these telomeres, but its activity declines significantly with age in most human tissues.
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